Human monoclonal antibodies by immortalization of memory B cells

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Monoclonal Antibodies

SUMMARY Monoclonal Antibodies are identical antibodies and Can be generated in ultimated amounts by countinuos cultures of single antibody- secreting cells. These cell lines are produced by cell fusion of normal lymphocytes to cells of a myeloma tumor cell line, which confers on the antibody producing hybrid cell, immortality and the ability grow as atumor in animals. monoclonal antibodies c...

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ژورنال

عنوان ژورنال: Current Opinion in Biotechnology

سال: 2007

ISSN: 0958-1669

DOI: 10.1016/j.copbio.2007.10.011